2-Deoxy-D-glucose - CAS 154-17-6
Not Intended for Therapeutic Use. For research use only.
Category:
Inhibitor
Product Name:
2-Deoxy-D-glucose
Catalog Number:
154-17-6
Synonyms:
2-Deoxy-D-arabino-hexose; D-Arabino-2-deoxyhexose
CAS Number:
154-17-6
Description:
2-deoxy-D-Glucose is a non-metabolizable glucose analog that inhibits phosphorylation of glucose by hexokinase, the first step of glycolysis. This results in the depletion in cellular ATP, the inhibition of protein glycosylation, and the disruption of ER quality control by inducing the unfolded protein response. 2-deoxy-D-Glucose has been shown to cause cell cycle inhibition and cell death in in vitro models of hypoxia, induce autophagy, increase reactive oxygen species production, activate AMPK, and block tumor cell growth in animal models.
Molecular Weight:
164.16
Molecular Formula:
C6H12O5
COA:
Inquire
MSDS:
Inquire
Targets:
Hexokinase
Chemical Structure
CAS 154-17-6 2-Deoxy-D-glucose

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