1.Disabled children's functionality and their mother's Quality of life and psychological status.
Yıldız A1, Tarakcı D2, Hajebrahimi F1, Mutluay F1. Pediatr Int. 2016 Apr 16. doi: 10.1111/ped.13020. [Epub ahead of print]
BACKGROUND AND AIMS: Physiotherapy is being provided for different disabled groups in pediatric rehabilitation centers. The Quality of Life (QOL) and psychological status in mothers of these children is affecting their compliance on rehabilitation period. The aim of this study was to assess the relationship between disability level of individuals receiving rehabilitation and their mother's QOL, psychological status and influencing factors.
2.Invasive Streptococcus pneumoniae in Canada, 2011-2014: Characterization of new candidate 15-valent pneumococcal conjugate vaccine serotypes 22F and 33F.
Golden AR1, Adam HJ2, Zhanel GG3; Canadian Antimicrobial Resistance Alliance (CARA). Vaccine. 2016 Apr 13. pii: S0264-410X(16)30041-X. doi: 10.1016/j.vaccine.2016.03.058. [Epub ahead of print]
Emerging non-PCV-13 Streptococcus pneumoniae serotypes 22F and 33F are included in a new 15-valent pneumococcal conjugate vaccine currently undergoing clinical trials in the United States. This study assessed the antimicrobial resistance and genetic relatedness of these two emerging pneumococcal serotypes. Of the 5075 invasive pneumococcal isolates collected in Canada from 2011 to 2014, 9.8% (497/5075) were serotype 22F and 3.2% (160/5075) were serotype 33F. Despite being among the top 4 most common serotypes collected each study year, serotype 22F demonstrated ≥98% susceptibility to all antimicrobials tested except clarithromycin and few were multi-drug resistant (MDR) (0.8%, 4/497). Serotype 22F isolates were highly clonal (ST433), with two isolates showing high relatedness to MDR international clone Sweden15A-25 (ST63). Conversely, serotype 33F showed greater antimicrobial resistance, greater genetic diversity and a higher proportion of MDR isolates (8.
3.A Pycnoporus sanguineus laccase for denim bleaching and its comparison with an enzymatic commercial formulation.
Iracheta-Cárdenas MM1, Rocha-Peña MA2, Galán-Wong LJ3, Arévalo-Niño K4, Tovar-Herrera OE5. J Environ Manage. 2016 Apr 13;177:93-100. doi: 10.1016/j.jenvman.2016.04.008. [Epub ahead of print]
A laccase from the basidiomycete Pycnoporus sanguineus strain RVAN5 was evaluated for its ability to decolorize synthetic dyes and denim bleaching. Dye color reduction and denim bleaching were monitored at different dye concentrations and incubation times. Dye decolorization by Pycnoporus sanguineus fungal crude extract (FCE) ranged from 80 to 96% within 2-4 h at 25-65 °C. Comparable results were obtained when violuric acid (VA) was added as mediator to the FCE, however, the number of decolorized dyes increased significantly. Dye decolorization rates with VA varied of initial and final optical density (595 nm) values of 2.5-3.0 and 0.2-0.02, respectively. P. sanguineus FCE had no substantial effect on denim bleaching when used alone, notwithstanding, the mixture of FCE with VA (10 mM) showed significant denim color reduction values and considerably higher than those obtained with a bleaching enzyme from a commercial formulation; CIElab values obtained with FCE/VA mixture were of ΔL = 6.
4.The impact of force on the timing of bruises evaluated in a porcine model.
Barington K1, Jensen HE2. J Forensic Leg Med. 2016 Apr 2;40:61-66. doi: 10.1016/j.jflm.2016.03.005. [Epub ahead of print]
In animal models developed in order to estimate the age of bruises, focus has been on the changes over time and not considering the force used to inflict the trauma. In the present study, gross and histological changes in 2, 4, 6 and 8 h old bruises which were inflicted with a low, moderate and high force were compared. Twelve experimental pigs were randomly assigned to three groups of force (low, moderate and high force). All pigs were anesthetized, and on each animal four blunt traumas were inflicted on the back with the low, moderate or high force according to the groups. The pigs were kept in anesthesia for 2, 4, 6 or 8 h, after which they were euthanized, and skin and muscle tissues were sampled for histology. As control, two pigs were included. The gross appearance of bruises developed similarly until 0.5 h after infliction at which time the visibility of the bruises depended on the force. The infiltration of subcutaneous neutrophils depended on the time and force used which was confirmed by both manual evaluation and image analysis of immunostained skin sections.