2,3,4,6-Tetra-O-benzoyl-a-D-mannopyranosyl trichloroacetimidate - CAS 183901-63-5
Category:
Carbohydrates
Product Name:
2,3,4,6-Tetra-O-benzoyl-a-D-mannopyranosyl trichloroacetimidate
CAS Number:
183901-63-5
Molecular Weight:
740.98
Molecular Formula:
C36H28Cl3NO10
COA:
Inquire
MSDS:
Inquire
Structure:
Monosaccharides
Chemical Structure
CAS 183901-63-5 2,3,4,6-Tetra-O-benzoyl-a-D-mannopyranosyl trichloroacetimidate

Related Monosaccharides Products


Reference Reading


1.Synthesis of mannose-containing analogues of (1-->6)-branched (1-->3)-glucohexaose.
Wu Z1, Kong F. Carbohydr Res. 2004 Jan 22;339(2):377-84.
Coupling of the trisaccharide acceptor 2,4,6-tri-O-acetyl-beta-D-glucopyranosyl-(1-->3)-[2,3,4,6-tetra-O-benzoyl-beta-D-glucopyranosyl-(1-->6)]-5-O-acetyl-1,2-O-isopropylidene-alpha-D-glucofuranose (2) with the trisaccharide donor 2,3,4,6-tetra-O-benzoyl-alpha-D-annopyranosyl-(1-->3)-[2,3,4,6-tetra-O-benzoyl-beta-D-glucopyranosyl-(1-->6)]-2,4-di-O-acetyl-alpha-D-glucopyranosyl trichloroacetimidate (1) gave an alpha-linked hexasaccharide 3, while coupling of 2 with the trisaccharide donor 2,3,4,6-tetra-O-benzoyl-alpha-D-mannopyranosyl-(1-->3)-[2,3,4,6-tetra-O-benzoyl-alpha-D-mannopyranosyl-(1-->6)]-2,4-di-O-acetyl-alpha-D-glucopyranosyl trichloroacetimidate (7) produced alpha- 8 and beta-linked 12 hexasaccharides in a ratio of 3:2. Deprotection of 3, 8, and 12 afforded the analogues of the immunomodulator beta-D-Glcp-(1-->3)-[beta-D-Glcp-(1-->6)]-alpha-D-Glcp-(1-->3)-beta-D-Glcp-(1-->3)-[beta-D-Glcp-(1-->6)]-D-Glcp (A).