2-(1,1'-biphenyl-4-yl)-1,2,4-triazole(5,1-a)isoquinoline - CAS 75318-62-6
Category:
Main Product
Product Name:
2-(1,1'-biphenyl-4-yl)-1,2,4-triazole(5,1-a)isoquinoline
Catalog Number:
75318-62-6
Synonyms:
2-(1,1'-biphenyl-4-yl)-1,2,4-triazole(5,1-a)isoquinoline
CAS Number:
75318-62-6
Molecular Weight:
0
Molecular Formula:
C22H15N3
COA:
Inquire
MSDS:
Inquire
Chemical Structure
CAS 75318-62-6 2-(1,1'-biphenyl-4-yl)-1,2,4-triazole(5,1-a)isoquinoline

Reference Reading


1.2-(1,1'-Biphenyl-4-yl)- 1,2,4-tria
Galliani G, Guzzi U, Tarzia G, Assandri A. J Vet Pharmacol Ther. 1986 Sep;9(3):246-53.
In the search for second generation post-coital pregnancy terminating agents belonging to the class of 2-phenyl-triazole[5,1-a]isoquinolines, the contragestational profile of (1,1'-biphenyl)-4-yl-1,2,4-triazole[5,1-a]isoquinoline, referred to as L 14105, was investigated in hamsters, rats, and bitches. Following subcutaneous or intramuscular administration in oily vehicles, L 14105 shows a very high anti-fertility activity in the three animal species, being from 1.8 to 2.5 times more effective than the parent drug, DL 717-IT. Unlike DL 717-IT, L 14105 possesses a high activity when administered by the oral route. The results obtained in the bitch make it confirm its potential use as a new orally active agent for the interruption of unwanted pregnancies.