|Description||Hydrastine, a natural alkaloid compound, could be used as a dopamine biosynthesis inhibitor.|
HUHS015 is a potent PCA-1/ALKBH3 inhibitor both in vitro and in vivo. The bioavailability (BA) of HUHS015 was 7.2% in rats after oral administration. As expect...
Sarolaner is an antiparasitic agent. It is used as veterinary drug.
Quillaic acid is the major aglycone of the widely studied saponins of the Chilean indigenous tree Quillaja saponaria Mol and can elicit dose-dependent antinocic...
HQ-415 is a relevant bioactive metal chelators(EC50=15 μM)
Macranthoidin B, a triterpenoid saponin compound, could be isolated from flowerbuds of Lonicera and has been found to have potential effect against inflammation...
Prednisolone hemisuccinate is a metabolite of a derivative of cortisol called Prednisolone. It can be used to treat a variety of inflammatory and auto-immune co...
MK436 is an anti-protozoal drug has been found to be effective against Trypanosoma cruzi infections.
Zamicastat is a potent and selective dopamine β-mono-oxygenase inhibitor. It prevents the Deterioration of Cardiometabolic and Inflammatory Biomarkers in a Gene...
Dorzolamide is a potent carbonic anhydrase II inhibitor with an IC50 value of 0.16 nM on human erythrocyte carbonic anhydrase II in vitro. It has been found to ...
Elamipretide is a cardiolipin peroxidase inhibitor and mitochondria-targeting peptide under the development of Stealth BioTherapeutics. It can Improve left Vent...
Carbidopa is an aromatic-L-amino-acid decarboxylase inhibitor with an IC50 of 29 ± 2 μM.
Naloxone is a medication used to block the effects of opioids, especially in overdose useful both in acute opioid overdose and in reducing respiratory or mental...
Letrozole is a third generation inhibitor of aromatase with IC50 of 0.07-20 nM.
Neobavaisoflavone significantly inhibited the production of reactive oxygen species (ROS), reactive nitrogen species (RNS) and cytokines: IL-1β, IL-6, IL-12p40,...
Glycodiazine is a sulfapyrimidine derivative with antihyperglycemic activity used in biological activities to predict human intestinal absorption in drug discov...
Glucagon, a peptide compound, is effective in increasing the glucose concentration in bloodstream and could be released by pancrea α cells.
CI 600 is a bio-active chemical, but no detailed information has been published yet.
CP-640186 is a potent inhibitor of mammalian ACCs and can reduce body weight and improve insulin sensitivity in test animals. It has recently been shown to be a...
Epimedin B, a flavonoids natural product extracted from Herbal Epimedium, has been studied to have potential antiosteoporotic effect.