(1R,2R)-(-)-2-Amino-1-cyclopentanecarboxylic acid - CAS 136315-77-0
Category:
Main Product
Product Name:
(1R,2R)-(-)-2-Amino-1-cyclopentanecarboxylic acid
Catalog Number:
136315-77-0
Synonyms:
Cyclopentanecarboxylic acid, 2-amino-, (1R,2R)- (9CI); (1R,2R)-2-AMINO-CYCLOPETANECARBOXYLIC ACID; (1R,2R)-(-)-2-Amino-1-cyclopentanecarboxylic acid
CAS Number:
136315-77-0
Molecular Weight:
129.16
Molecular Formula:
C6H11NO2
COA:
Inquire
MSDS:
Inquire
Canonical SMILES:
C1CC(C(C1)N)C(=O)O
InChI:
InChI=1S/C6H11NO2/c7-5-3-1-2-4(5)6(8)9/h4-5H,1-3,7H2,(H,8,9)/t4-,5-/m1/s1
InChIKey:
JWYOAMOZLZXDER-RFZPGFLSSA-N
Chemical Structure
CAS 136315-77-0 (1R,2R)-(-)-2-Amino-1-cyclopentanecarboxylic acid

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Reference Reading


1.[New enzymatic strategies for enantiomers of lactams and amino acids].
Forró E1. Acta Pharm Hung. 2011;81(3):125-33.
To fulfil the requirements of modern go-ahead research, new direct and indirect enzymatic strategies and new techniques have been devised for the preparation of enantiopure beta- and gamma-lactams and beta- and gamma-amino acids, and some of them have been scaled up. For example, a formal total synthesis of enantiopure Anatoxina, a neurotoxic alkaloid, but a potent and stereospecific agonist at nicotinic acetylcholine receptors has been introduced. An efficient and very simple method has been developed for the synthesis of the antibacterial cispentacin [(1R,2S)-2-amino-1-cyclopentanecarboxylic acid] and 8 new derivatives. A highly efficient enzymatic procedure has been elaborated for the synthesis of the blockbuster drug Abacavir and Carbovir intermediate (1S,4R)-4-aminocyclopent-2-ene-1-carboxylic acid. The first enzymatic method has been devised for the synthesis of (R)-3-amino-4-(2,4,5-trifluorophenyl)butanoic acid, the intermediate for the new antidiabetic drug Sitagliptine.