(1H-indol-2-ylmethyl)amine - CAS 21109-25-1
Category:
Main Product
Product Name:
(1H-indol-2-ylmethyl)amine
Catalog Number:
21109-25-1
Synonyms:
AKOS B014368; (1H-INDOL-2-YLMETHYL)AMINE; (1H-INDOL-2-YL)METHANAMINE; 1-(1H-INDOL-2-YL)METHANAMINE; ART-CHEM-BB B014368; ART-CHEM-BB B016014
CAS Number:
21109-25-1
Molecular Weight:
146.19
Molecular Formula:
C9H10N2
Quantity:
Data not available, please inquire.
COA:
Inquire
MSDS:
Inquire
Canonical SMILES:
C1=CC=C2C(=C1)C=C(N2)CN
InChI:
InChI=1S/C9H10N2/c10-6-8-5-7-3-1-2-4-9(7)11-8/h1-5,11H,6,10H2
InChIKey:
RNAODKZCUVVPEN-UHFFFAOYSA-N
Chemical Structure
CAS 21109-25-1 (1H-indol-2-ylmethyl)amine

Related Products


Reference Reading


1.Potential histamine H2-receptor blockers. 3- and 2-indole derivatives as immobile analogues of tautomeric forms of cimetidine.
Tecle H, Robichaud L, Schwender CF. J Med Chem. 1981 Sep;24(9):1095-7.
At physiological pH, cimetidine (1a) and its analogues burimamide (1b) and metiamide (1c) exist mainly as an equilibrium mixture of tautomers. A high concentration of tautomer 2 is associated with increased H2-receptor interaction. 3-Indole derivatives (5c-f) and 2-indole derivatives (6c-f) were synthesized and tested as immobile analogues of tautomers 2 and 3, respectively. Weak competitive H2 antagonism was found in N'-cyano-N-[2-[(1H-indol-3-ylmethyl)thio]ethyl]carbamidothioic acid methyl ester (5e) and N-[2-[(1H-indol-2-ylmethyl)thio]-ethyl]-N'-methylthiourea (6c).