PNU-159682 is a major active metabolite of nemorubicin (MMDX) in human liver microsomes. PNU-159682 showed > 3,000-fold cytotoxic than its parent compound(MMDX ...
An antiarrhythmic of 1-st and 1Y classes and a blocker of TTX sensitive Na+ channels, Ca++ antagonist diterpene alkaloid from Delphinium staphisagria.
Polyprenols are natural long-chain isoprenoid alcohols of the general formula H-(C5H8)n-OH where n is the number of isoprene units. Any prenol with more than 4 ...
DM3 is a cytotoxic agent. It is used as the cytotoxic component in antibody-drug conjugates.
7-Epi 10-Desacetyl Paclitaxel
7-Epi 10-Desacetyl Paclitaxel is a derivative of Paclitaxel, which is a microtubule polymer stabilizer with IC50 of 0.1 pM in human endothelial cells.
10-Deacetyl-7-xylosyl paclitaxel is a Paclitaxel derivative with improved pharmacological features and higher water solubility.
Quinoline Alkaloid Extracted from Haplophyllum bucharicum
Calciseptine is a natural neurotoxin isolated from the black mamba Dendroaspis p. polylepis venom. This toxin consists of 60 amino acids with four disulfide bon...
PBD dimer is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.
Iron carrier Synthetic
Synthetic, a potent inhibitor of high-affinity choline uptake (HAChU) in synaptosomes.
Potent, reversible acetylcholinesterase inhibitor
Monomethyl Auristatin E (MMAE) is a synthetic analog of dolastatin 10 that similarly inhibits tubulin polymerization and exhibits potent cytotoxicity. It is com...
Potent ganglioblocker, a neuronal nicotinic AChR antagonist. .
Cloflubicyne is a potent non-competitive GABA antagonist, convulsant, laboratory insecticide.
Selective blocker of the big conductance Ca2+-activated K+ channel.
Harmaline is a fluorescent psychoactive indole alkaloid from the group of harmala alkaloids and beta-carbolines. It is the partially hydrogenated form of harmin...
A scorpion alpha-insect toxin, which prolongs the evoked action potential by an inhibition of sodium current inactivation in insects and mammals.
Known as a weak hypotensive, moderate M- and N-cholinolytic pyrrolizidine alkaloid, xtracted from Trachelanthus Korolkowia.
Sevedindione presents an antiarrhythmic activity on arrhythmias caused by Aconitine.