A selective inhibitor of endoplasmic reticulum Ca2+-ATPase.
Scyllatoxin (Leiurotoxin-1) is a neurotoxin that was originally isolated from Leiurus quinquestriatus hebraeus. Scyllatoxin binds and blocks SK channels (small ...
Tropane alkaloid, from plants of the Convolvulus genus,
A diterpenoid alkaloids from plants of the Aconitum and Delphinium species, selective blocker of the TTX-sensitive Na+ channel in the heart; potent antiarrhythm...
Staurosporine is broad spectrum protein kinase inhibitor. Enzymes inhibited include protein kinase C (IC50 = 3 nM), protein kinase A (IC50 = 7 nM), p60v-src tyr...
Bicyclic analog of Ach, a weak muscarinic AChR agonist.
DM4 is a cytotoxic agent. It is used as the cytotoxic component in antibody-drug conjugates.
Duocarmycin B1 is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.
Seco-Duocarmycin GA is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.
Synthetic., a GABA-gated chloride channel blocker, non-competitive GABA antagonist in mammals.
Melittin inhibits protein kinase C, Ca2+/calmodulin-dependent protein kinase II, myosin light chain kinase and Na+/K+-ATPase (synaptosomal membrane) and is a ce...
Amaryllidaceae alkaloid from plants of the Amaryllidaceae family. A hypotensive, sedative. Amaryllidaceae alkaloid , from plants of the Amaryllidaceae family.
A selective blocker of the delayed rectifier K+ channel found in virtual screening
DM1 is a cytotoxic agent. It is used as the cytotoxic component in antibody-drug conjugates.
Dihydropyridine calcium channel blocker. Antianginal; antihypertensive.
Nitrodienamine, an inhibitor of Ca2+/Mg2+ ATPase.
A spasmolytic agent, shows pharmacol. props. similar to 2-(Methylamino)-1-phenyl-1-propanol BCJ45-G.
Cervane alkaloid derivative of Imperialine from the plant Petilium eduardi. A selective M2 muscarinic receptor antagonist.
Mebicyphat is shown to be a non-competitive GABA antagonist. Blocks GABA gated Cl- channels, and is shown to inhibit dihydropicrotoxin
A neuronal nicotinic AChR antagonist, blocking superior cervical sympathetic ganglion