1-OCTANESULFONIC ACID, SODIUM SALT, MONOHYDRATE - CAS 207596-29-0
Catalog number:
207596-29-0
Category:
Main Product
Molecular Formula:
C8H19NaO4S
Molecular Weight:
234.29
COA:
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Purity:
≥99%
Appearance:
white fine powder
Synonyms:
1-OCTANESULFONIC ACID, SODIUM SALT, MONOHYDRATE; SODIUM 1-OCTANESULFONATE MONOHYDRATE; 1-OCTANESULFONIC ACID SODIUM SALT MONO-H YDRATE, FOR IPC; Sodium octane-1-sulfonate monohydrate; 1-Octanesulfonic acid sodium salt monohydrate, 99+%; 1-Octanesulfonic acid
MSDS:
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Melting Point:
300ºC
InChIKey:
MBURIAHQXJQKRE-UHFFFAOYSA-M
InChI:
InChI=1S/C8H18O3S.Na.H2O/c1-2-3-4-5-6-7-8-12(9,10)11;;/h2-8H2,1H3,(H,9,10,11);;1H2/q;+1;/p-1
Canonical SMILES:
CCCCCCCCS(=O)(=O)[O-].O.[Na+]
1.Influence of lipophilic counter-ions in combination with phloretin and 6-ketocholestanol on the skin permeation of 5-aminolevulinic acid.
Auner BG1, Valenta C, Hadgraft J. Int J Pharm. 2003 Apr 14;255(1-2):109-16.
In this study, the effect of lipophilic counter-ions on the permeation of 5-aminolevulinic acid (ALA) in combination with skin impregnation by phloretin and 6-ketocholestanol was evaluated. Standard in vitro permeation experiments with porcine skin were performed analysing the ALA content by HPLC and fluorescent detection after ALA derivatisation. The shake flask method in combination with a trinitrobenzensulfonic acid test for ALA analysis was performed to calculate the apparent partition coefficient (logP(Oct)). The permeation of ALA was enhanced by cetylpyridinium chloride and benzalkonium chloride at pH 7.0 and by sodium-1-octanesulfonic acid, sodium-1-heptanesulfonic acid and sodium-1-pentanesulfonic acid monohydrate at pH 4.0. Corresponding effects of these additives were observed on the partitioning of ALA. Pre-impregnation of porcine skin with phloretin and 6-ketocholestanol increased the ALA diffusion about 1.7-fold at pH 7.0. Moreover, this transport enhancement by 6-ketocholestanol was 3.
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CAS 207596-29-0 1-OCTANESULFONIC ACID, SODIUM SALT, MONOHYDRATE

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