1-Deoxynojirimycin hydrochloride - CAS 73285-50-4
Not Intended for Therapeutic Use. For research use only.
Category:
Inhibitor
Product Name:
1-Deoxynojirimycin hydrochloride
Catalog Number:
73285-50-4
Synonyms:
(2R,3R,4R,5S)-2-(Hydroxymethyl)-3,4,5-piperidinetriol Hydrochloride; 1-Deoxynojirimycin Hydrochloride; AT 2220; Duvoglustat Hydrochloride; Moranoline Hydrochloride; DNJ Hydrochloride
CAS Number:
73285-50-4
Description:
1-Deoxynojirimycin, also called Duvoglustat, is produced by Bacillus species. It is a glucose analog that can inhibit α-glucosidase I and II. 1-Deoxynojirimycin can prevent the formation of complex N-linked oligosaccharides in yeast and intact mammalian cells through inhibiting both α-glucosidase I and II. The IC50 values are ~2 µM. Phase II clinical development of duvoglustat for Glycogen storage disease type II is ongoing
Molecular Weight:
199.63
Molecular Formula:
C6H13NO4.HCl
Quantity:
Milligrams-Grams
Quality Standard:
In-house standard
COA:
Inquire
MSDS:
Inquire
Canonical SMILES:
C1C(C(C(C(N1)CO)O)O)O.Cl
InChI:
InChI=1S/C6H13NO4.ClH/c8-2-3-5(10)6(11)4(9)1-7-3;/h3-11H,1-2H2;1H/t3?,4?,5-,6+;/m1./s1
InChIKey:
ZJIHMALTJRDNQI-NTBRWAQFSA-N
Targets:
α- and β-glucosidases
Current Developer:
Originator Amicus Therapeutics
Chemical Structure
CAS 73285-50-4 1-Deoxynojirimycin hydrochloride

Related α- and β-glucosidases Products


CAS 73285-50-4 1-Deoxynojirimycin hydrochloride

1-Deoxynojirimycin hydrochloride
(CAS: 73285-50-4)

1-Deoxynojirimycin, also called Duvoglustat, is produced by Bacillus species. It is a glucose analog that can inhibit α-glucosidase I and II. 1-Deoxynojirimycin...

CAS 79831-76-8 Castanospermine

Castanospermine
(CAS: 79831-76-8)

Castanospermine is an inhibitor of all forms of α- and β-glucosidases, especially glucosidase l. It inhibits lysosomal and neutral α-glucosidases with Ki values...