Known as a weak hypotensive, moderate M- and N-cholinolytic pyrrolizidine alkaloid, xtracted from Trachelanthus Korolkowia.
An antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin.
A terpenoid complex ester , from plants of the Umbelliferae family, a substance presenting an estrogenic activity.
Cervane alkaloid derivative of Imperialine from the plant Petilium eduardi. A selective M2 muscarinic receptor antagonist.
7-Epi 10-Desacetyl Paclitaxel
7-Epi 10-Desacetyl Paclitaxel is a derivative of Paclitaxel, which is a microtubule polymer stabilizer with IC50 of 0.1 pM in human endothelial cells.
Fraxinellone is an insecticidal agent, inhibiting growth of larvae, used in the treatment and protection of crops and produce. Also, a naturally occurring compo...
Idarubicin is an anthracycline antibiotic and a DNA topoisomerase II (topo II) inhibitor for MCF-7 cells with IC50 of 3.3 ng/mL.
Muscarinic toxin 2
Muscarinic toxin 2 (MT2) is one member of a family of small peptides of 65 amino acid residues of around 7076 daltons in molecular weight derived from the venom...
Bicyclic diterpenoid of the clerodane series
Anticoagulant: irreversible inhibits serine proteinase a-thrombine. Fluorocontaining phosphonate, synthetised.
Norfluorocurarine is a peripheral vasodilator that increases blood flow to the brain (sold under the trademark Oxybral SR) .<br/>Generic drugs containing vincam...
Synthetic, a potent inhibitor of high-affinity choline uptake (HAChU) in synaptosomes.
Long-acting, centrally active acetylcholinesterase inhibitor (IC50 = 410 nM) and allosteric potentiator at neuronal nicotinic ACh receptors. Prevents β-amyloid-...
Extrat from the seeds of Corchorus olitoriu, a cardiac Glycoside.
a non specific stimulant of immunogenesis; also used for erytrocytes hemolysis and automatic leucocyte numbering. Triterpene saponine, mixture of 4 glycosides f...
Steroidal Alkaloid from Convolvulus krauseanus
A muscarinic receptors antagonist.
Photosensitizing; used for determining DNA/RNA structures in cells and microorganisms. Furocoumarin , from plants of the Psoralea genus, Leguminosae.
Amiloride HCl is a relatively selective inhibitor of the epithelial sodium channel, used in the management of hypertension and congestive heart failure.
Microcystin-LR is a selective inhibitor of protein phosphatase 2A (PP2A) (IC50= 0.04 nM) and will completely inhibit this enzyme without affecting PP1 when used...