(1,3-DIHYDRO-ISOINDOL-2-YL)-ACETIC ACID - CAS 363165-80-4
Category:
Main Product
Product Name:
(1,3-DIHYDRO-ISOINDOL-2-YL)-ACETIC ACID
Catalog Number:
363165-80-4
Synonyms:
CHEMBRDG-BB 4003155; AKOS BB-9356; (1,3-DIHYDRO-ISOINDOL-2-YL)-ACETIC ACID; 1,3-DIHYDRO-2H-ISOINDOL-2-YLACETIC ACID; UKRORGSYN-BB BBV-182318
CAS Number:
363165-80-4
Molecular Weight:
177.2
Molecular Formula:
C10H11NO2
COA:
Inquire
MSDS:
Inquire
Canonical SMILES:
C1C2=CC=CC=C2CN1CC(=O)O
InChI:
InChI=1S/C10H11NO2/c12-10(13)7-11-5-8-3-1-2-4-9(8)6-11/h1-4H,5-7H2,(H,12,13)
InChIKey:
HZUNEPIRTFDGOT-UHFFFAOYSA-N
Chemical Structure
CAS 363165-80-4 (1,3-DIHYDRO-ISOINDOL-2-YL)-ACETIC ACID

Reference Reading


1.DNA hybridization electrochemical sensor using conducting polymer.
Cha J1, Han JI, Choi Y, Yoon DS, Oh KW, Lim G. Biosens Bioelectron. 2003 Sep;18(10):1241-7.
We report the use of poly(thiophen-3-yl-acetic acid 1,3-dioxo-1,3-dihydro-isoindol-2-yl ester (PTAE) for application to electrochemical hybridization sensor. A synthetic route for the thiophen-3-yl-acetic acid 1,3-dioxo-1,3-dihydro-isoindol-2-yl ester (TAE) is described, which is used as a monomer of conducting polymer sensor. A direct chemical substitution of probe oligonucleotide to good leaving group site in the PTAE is carried out on the conducting polymer film. A biological recognition can be monitored by comparison with the electrochemical signal (cyclic voltammogram) of single and double strand state oligonucleotide. The sensitivity of the electrochemical sensor is 0.62 microA/nmole and the detection limit is 1 nmole. The oxidation current of double strand state oligonucleotide is a half of that of single strand, that is corresponding to the decrease of electrochemical activity of conducting polymer with increase of stiffness of side group of the polymer.