1,1,3-TRIMETHYLTETRALIN - CAS 85268-66-2
Catalog number: 85268-66-2
Category: Main Product
Molecular Formula:
C13H18
Molecular Weight:
174.28
COA:
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Purity:
95%
Synonyms:
1,1,3-TRIMETHYLTETRALIN
MSDS:
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1.Diversity and Tropism of HIV-1 Plasma Rebound Virus after Treatment Discontinuation.
Bednar MM1, Hauser BM1, Zhou S1, Jacobson JM2, Eron JJ Jr3, Frank I4, Swanstrom R5. J Infect Dis. 2016 Apr 30. pii: jiw172. [Epub ahead of print]
HIV-infected people discontinuing therapy experience a rebound of virus from a persistent reservoir. We examined 10 rebound samples from ACTG study A5068 using single genome amplification and Primer ID deep sequencing to assess env genetic diversity of rebounding virus. Most rebound virus populations showed significant diversity. All env genes examined required high levels of CD4 for entry, consistent with selection of replication in CD4+ T cells. These results indicate that most people discontinuing therapy release a diverse population of virus, and this released virus has entry features of virus selected for replication in CD4+ T cells rather than myeloid cells.
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CAS 85268-66-2 1,1,3-TRIMETHYLTETRALIN

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