1,1,1-Nitrilotris-2-propanol - CAS 122-20-3
Catalog number: 122-20-3
Category: Main Product
Molecular Formula:
C9H21NO3
Molecular Weight:
191.26794;g/mol
COA:
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Purity:
95%
Appearance:
clear to light yellow liquid
Synonyms:
Triisopropanolamine; TIPA; 122-20-3; TRIS(2-HYDROXYPROPYL)AMINE; Tri-2-propanolamine; Tri-iso-propanolamine
MSDS:
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Quantity:
Data not available, please inquire.
Boiling Point:
190ºC (23 mmHg)
Melting Point:
48-52ºC
Density:
1
InChIKey:
SLINHMUFWFWBMU-UHFFFAOYSA-N
InChI:
InChI=1S/C9H21NO3/c1-7(11)4-10(5-8(2)12)6-9(3)13/h7-9,11-13H,4-6H2,1-3H3
Canonical SMILES:
CC(CN(CC(C)O)CC(C)O)O
1.The prognostic value of plasma nesfatin-1 concentrations in patients with traumatic brain injury.
Wu GQ1, Chou XM2, Ji WJ2, Yang XG2, Lan LX2, Sheng YJ2, Shen YF2, Li JR2, Huang GZ2, Yu WH3, Dong XQ3, Du Q3, Yang DB3, Zhang ZY4, Wang H3, Shen YF3, Jiang L3. Clin Chim Acta. 2016 May 4. pii: S0009-8981(16)30205-4. doi: 10.1016/j.cca.2016.05.001. [Epub ahead of print]
BACKGROUND: Nesfatin-1 is related to inflammation. Its increased circulating concentrations are associated with the severity and prognosis of subarachnoid hemorrhage. In-hospital major adverse events (IMAEs), including acute traumatic coagulopathy, progressive hemorrhagic injury and posttraumatic cerebral infarction, are correlated with mortality after traumatic brain injury (TBI). The present study was designed to investigate the changes of plasma nesfatin-1 concentrations and further assess its association with inflammation, trauma severity, in-hospital mortality and IMAEs following TBI.
2.Identification of transmembrane helix 1 (TM1) surfaces important for EnvZ dimerisation and signal output.
Heininger A1, Yusuf R2, Lawrence RJ3, Draheim RR4. Biochim Biophys Acta. 2016 May 4. pii: S0005-2736(16)30144-4. doi: 10.1016/j.bbamem.2016.05.002. [Epub ahead of print]
The Escherichia coli sensor kinase EnvZ modulates porin expression in response to various stimuli, including extracellular osmolarity, the presence of procaine and interaction with an accessory protein, MzrA. Two major outer membrane porins, OmpF and OmpC, act as passive diffusion-limited pores that allow compounds, including certain classes of antibiotics such as β-lactams and fluoroquinolones, to enter the bacterial cell. Even though the mechanisms by which EnvZ detects and processes the presence of various stimuli are a fundamental component of microbial physiology, they are not yet fully understood. Here, we assess the role of TM1 during signal transduction in response to the presence of extracellular osmolarity. Various mechanisms of transmembrane communication have been proposed including rotation of individual helices within the transmembrane domain, dynamic movement of the membrane-distal portion of the cytoplasmic domain and regulated intra-protein unfolding.
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CAS 122-20-3 1,1,1-Nitrilotris-2-propanol

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